BiotechNews1

Originally published by Flinders University, on October 10, 2023 A schematic depicting the one-step argon atmospheric pressure plasma jet (Ar-APJ) process to transform S. maxima biomass into an ultrathin bioactive coating. A) S. maxima is sprayed onto a universal substrate. B) Ar-APJ process transforms the S. maxima biomass into a durable, bioactive, ultrathin coating. C) Antibacterial wound dressings as a proposed application for the Ar-APJ technology. Credit: Small (2023). DOI: 10.1002/smll.202305469 Researchers at Flinders University have taken a significant leap in the field of wound care using an innovative approach . By deploying an argon atmospheric plasma jet , they have successfully transformed Spirulina maxima , a blue-green microalgae , into ultrathin bioactive coatings . These coatings not only t ackle bacterial infections but als o promote faster wound healing and possess potent anti-inflammatory properties . This holds promise especially for the treatment of ch...

Originally published by Impact Journals LLC on October 25, 2023 Autophagy contributes to cells’ survival during chronological aging. Credit: Aging (2023). DOI: 10.18632/aging.205102 A new research paper titled "Live while the DNA lasts. The role of autophagy in DNA loss and survival of diploid yeast cells during chronological aging " has been published in Aging . Aging is inevitable and affects all cell types. Thus, yeast cells are often used as a model in aging studies. There are two approaches to studying aging in yeast : replicative aging , which describes the proliferative potential of cells, and chronological aging , which is used for studying post-mitotic cells. In this new study, while analyzing the chronological lifespan (CLS) of diploid Saccharomyces cerevisiae cells, researchers Tuguldur Enkhbaatar, Marek Skoneczny, Karolina Stępień, Mateusz Mołoń, and Adrianna Skoneczna from the Polish Academy of Sciences and Rzeszów University discovered a remar...

Originally published by Hudson Institute of Medical Research, on October 20, 2023 Associate Professor Samuel Forster from Hudson Institute of Medical Research is developing new ways of understanding interactions within the human gut microbiome. Credit: Hudson Institute of Medical Research The more diverse species in your gut, the better it is for your health. Now an international team led by the Hudson Institute of Medical Research has found a way to determine which species are important and how they interact to create a healthy microbiome . Understanding these relationships opens the door to a new world of medical opportunities for conditions from inflammatory bowel disease to infections , autoimmune diseases and cancer s. Associate Professor Samuel Forster and his team at Hudson Institute of Medical Research, working with collaborators from the Institute for Systems Biology in the U.S. and local collaborators at Monash University and Monash Health, have spent years stud...

Published by Thamarasee Jeewandara , Medical Xpress, on October 16, 2023 Schematic of the combination of EarCartilage and EarSkin. (A) EarSkin was prepared by creating a dermal layer fabricated out of human fibroblasts and human dermal microvascular endothelial cells (HDMECs) in a collagen I hydrogel. Once matured, an epidermal layer of human keratinocytes and melanocytes was seeded on top of the dermal part. (B) EarCartilage was fabricated using a hyaluronan transglutaminase (HATG)–based bioink together with primary human auricular chondrocytes. Postprinting constructs can be enzymatically crosslinked using calcium-triggered enzymatic crosslinking of factor XIII (30). (C) Experimental timeline of EarCartilage and EarSkin in vivo. EarCartilage was matured for 17 weeks before implantation. EarSkin was created by combining fibroblasts and HDMECs in a collagen I hydrogel and matured for two weeks before seeding keratinocytes and melanocytes on top and culturing it for an additional ...