Study unveils improved mRNA cancer vaccine targeting

Originally published by Chris Kocher, Binghamton University, in MedicalExpress on December 10, 2025

Edited by Stephanie Baum, reviewed by Andrew Zinin

Credit: Theranostics (2026). DOI: 10.7150/thno.123633

No matter where cancer cells grow in the human body, they are a threat to our health and our lives. But instead of treating them with chemotherapy or radiation—which have undesirable side effects—what if we could train our own immune systems to kill the rogue cells?

That's the idea behind mRNA cancer vaccines, which build on science learned from COVID-19 vaccines to address an even larger health concern.

Writing in Theranostics, Binghamton University Associate Professor Yuan Wan and his collaborators outline a better way to target mRNA treatments. It builds on Wan's work over the past five years to develop a better delivery method for chemotherapy medications.

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