Proteomic profile study reveals signatures for distinguishing different forms of Alzheimer's disease


Originally published by Justin Jackson , Medical Xpress, on July 6, 2023


 

Thinking about the time. Credit: Freeimages.com

Researchers at Washington University School of Medicine in St. Louis have identified proteomic changes associated with forms of Alzheimer's disease (AD). In a paper, "Proteomics of brain, CSF, and blood identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease," published in Science Translational Medicine, the researchers identify specific and shared proteomic changes associated with sporadic Alzheimer's disease (AD) across brain tissue, cerebrospinal fluid (CSF), and blood.

The findings show the potential of proteomic analysis to distinguish between different types of AD and act as a predictive model and biomarker of disease types. 

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