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Stress-reduction molecule has potential to treat aging and metabolic disorders

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Originally published by University of Queensland on January 22, 2026 edited by Lisa Lock , reviewed by Robert Egan University of Queensland researchers say the discovery of a new stress reduction role for a naturally occurring molecule in the body could lead to new drugs and treatment for metabolic disorders and aging .     Proposed model of miR-71 cell-autonomous and cell-non-autonomous dampening of mitochondrial stress responses. Credit: Nature Communications ( 2025 ). DOI: 10.1038/s41467-025-67198-2 Professor Steven Zuryn, a molecular geneticist from UQ's Queensland Brain Institute , was part of a team that found that very small RNA molecules , called microRNAs , bind to genes and prevent them from being over-activated . MicroRNAs were discovered in C. elegans about 30 years ago and have since been shown to be important in human health and disease . This initial discovery led to the 2024 Nobel Prize in Physiology or Medicine . Read more l   ...