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Link between gut microbiota and Parkinson's disease points to potential therapeutic route

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Originally published by Nagoya University, on June 17, 2024   In Parkinson's disease, a reduction in the gut bacteria of genes responsible for synthesizing the essential B vitamins B2 and B7 was found. Credit: Reiko Matsushita A study led by Nagoya University Graduate School of Medicine in Japan has revealed a link between gut microbiota and Parkinson's disease (PD) . The researchers found a reduction in the gut bacteria of genes responsible for synthesizing the essential B vitamins B2 and B7 . They also identified a relationship between the lack of these genes and low levels of agents that help maintain the integrity of the intestinal barrier. This barrier prevents toxins from entering the bloodstream , which c auses the inflammation seen in PD . Their findings , published in npj Parkinson's Disease , suggest that treatment with B vitamins to address these deficiencies can be used to treat PD . PD is characterized by a variety of physical symptoms that h...

Deep dive into the gut unlocks new disease treatments

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Originally published by Hudson Institute of Medical Research, on October 20, 2023 Associate Professor Samuel Forster from Hudson Institute of Medical Research is developing new ways of understanding interactions within the human gut microbiome. Credit: Hudson Institute of Medical Research The more diverse species in your gut, the better it is for your health. Now an international team led by the Hudson Institute of Medical Research has found a way to determine which species are important and how they interact to create a healthy microbiome . Understanding these relationships opens the door to a new world of medical opportunities for conditions from inflammatory bowel disease to infections , autoimmune diseases and cancer s. Associate Professor Samuel Forster and his team at Hudson Institute of Medical Research, working with collaborators from the Institute for Systems Biology in the U.S. and local collaborators at Monash University and Monash Health, have spent years stud...