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New enzyme allows CRISPR technologies to accurately target almost all human genes

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Originally published by Michaela Kane, Duke University, on December 5, 2023   Credit: Nature Chemical Biology (2023). DOI: 10.1038/s41589-023-01481-5 A team of engineers at Duke University have developed a method to broaden the reach of CRISPR technologies . While the original CRISPR system could only target 12.5% of the human genome, the new method expands access to nearly every gene to potentially target and treat a broader range of diseases through genome engineering. The research involved collaborators at Harvard University, Massachusetts Institute of Technology, University of Massachusetts Medical School, University of Zurich and McMaster University. This work was published on October 4 in the journal Nature Communications . CRISPR-Cas is a bacterial immune system that allows bacteria to use RNA molecules and CRISPR-associated (Cas) proteins to target and destroy the DNA of invading viruses. Since its discovery, researchers have raced to develop an arsenal of...

Newly discovered enzyme that turns air into electricity, providing a new clean source of energy

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  Published by Monash University on March 8, 2023   Credit: Pixabay/CC0 Public Domain.                                                             Australian scientists have discovered an enzyme that converts air into energy . The finding, published today in the journal Nature , reveals that this enzyme uses the low amounts of the hydrogen in the atmosphere to create an electrical current . This finding opens the way to create devices that literally make energy from thin air . The research team, led by Dr. Rhys Grinter , Ph.D. student Ashleigh Kropp , and Professor Chris Greening from the Monash University Biomedicine Discovery Institute in Melbourne , Australia, produced and analyzed a hydro...