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Link between gut microbiota and Parkinson's disease points to potential therapeutic route

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Originally published by Nagoya University, on June 17, 2024   In Parkinson's disease, a reduction in the gut bacteria of genes responsible for synthesizing the essential B vitamins B2 and B7 was found. Credit: Reiko Matsushita A study led by Nagoya University Graduate School of Medicine in Japan has revealed a link between gut microbiota and Parkinson's disease (PD) . The researchers found a reduction in the gut bacteria of genes responsible for synthesizing the essential B vitamins B2 and B7 . They also identified a relationship between the lack of these genes and low levels of agents that help maintain the integrity of the intestinal barrier. This barrier prevents toxins from entering the bloodstream , which c auses the inflammation seen in PD . Their findings , published in npj Parkinson's Disease , suggest that treatment with B vitamins to address these deficiencies can be used to treat PD . PD is characterized by a variety of physical symptoms that h