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Nobel Prize in medicine goes to trio for their work on immune tolerance

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Originally published By Patrick Pester in LiveScience on October 6, 2025 The 2025 Nobel Prize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their work on how our immune system is prevented from attacking our organs. The 2025 Nobel Prize for Physiology or Medicine winners, Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi, pioneered the field of peripheral immune tolerance . (Image credit: © The Nobel Committee for Physiology or Medicine. Ill. Mattias Karlén) A trio of researchers has won the 2025 Nobel Prize in Physiology or Medicine for discovering how the immune system is prevented from attacking our own bodies . Mary E. Brunkow of the Institute for Systems Biology in Seattle , Fred Ramsdell of Sonoma Biotherapeutics in San Francisco , and Shimon Sakaguchi of Osaka University in Japan were awarded the prize " for their discoveries concerning peripheral immune tolerance ." The Nobel Assembly at Karol...